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FBXW7/hCDC4 is a general tumor suppressor in human cancer
(2007)
The ubiquitin-proteasome system is a major regulatory pathway of protein degradation and plays an important role in cellular division. Fbxw7 (or hCdc4), a member of the F-box family of proteins, which are substrate recognition ...
Four novel germline mutations in the MLH1 and PMS2 mismatch repair genes in patients with hereditary nonpolyposis colorectal cancer
(2009)
Background: Hereditary nonpolyposis colorectal cancer (HNPCC) is the most common cause of early onset hereditary colorectal cancer. In the majority of HNPCC families, microsatellite instability (MSI) and germline mutation ...
Glutathione-S-transferase M1, T1 and P1 gene polymorphisms in type I autoimmune hepatitis: A case-control study [3]
(2007)
[No abstract available]
Gastro-oesophageal reflux disease and irritable bowel syndrome: A significant association in an Iranian population
(2008)
Background: Gastro-oesophageal reflux disease and irritable bowel syndrome are common diseases, which may be related. Aim: To assess the association between gastro-oesophageal reflux disease and irritable bowel syndrome ...
Age-specific seroprevalence of hepatitis A infection among children visited in pediatric hospitals of Tehran, Iran
(2004)
Background: Hepatitis A is an enterically transmitted disease that still remains endemic in many developing countries. In some countries improvements in living conditions have recently led to changing in epidemiology of ...
Appendectomy, tonsillectomy, and risk of inflammatory bowel disease: A case control study in Iran
(2006)
There is some controversy about the prevalence of appendectomy and tonsillectomy among patients with Crohn's disease and a lower rate of appendectomy among patients with ulcerative colitis (UC). The objective of this study ...
Association between MTHFR polymorphism (C677T) with nonfamilial colorectal cancer
(2009)
The enzyme 5,10-methylene-tetrahydrofolate reductase (MTHFR) is linked to DNA methylation, synthesis, and repair. C677T is one of the most important polymorphisms in the MTHFR gene. The single nucleotide polymorphism C677T ...
Knowledge of disease and health information needs of the patients with inflammatory bowel disease in a developing country
(2006)
Background and aims: This study was performed to have a first-time assessment on the knowledge level of a population of inflammatory bowel disease (IBD) patients in a developing country like Iran and to identify their ...
Liver, spleen, pancreas and kidney involvement by human fascioliasis: Imaging findings
(2004)
Background: Fasciola hepatica primarily involves the liver, however in some exceptional situations other organs have been reported to be involved. The ectopic involvement is either a result of Parasite migration or perhaps ...
Molecular epidemiology of Hepatitis Delta Virus (HDV) in Iran: A preliminary report
(2008)
To identify hepatitis delta virus (HDV) genetic variability and its circulating genotypes amongst infected Iranian patients, 25 patients with positive anti-HDV status from different parts of Iran were enrolled in this ...