Now showing items 1-3 of 3
Production and characterization of monoclonal antibodies against human IgG in Balb/c mouse
Immunoglobulin G (IgG) is the main immunoglobulin in natural human serum. It constitutes 70 to 75 percent of all immunoglobulins. Monoclonal antibodies have many applications in diagnosis, treatment and purification. The ...
Development and characterization of monoclonal antibodies against human epidermal growth factor receptor in Balb/c mice
For production of monoclonal antibody (mAb) against human epidermal growth factor receptor (EGFR), first, five female Balb/c mice 6 to 8 weeks old were immunized against A431 tumoral cells that express more EGFR on its ...
Target therapy of cancer: Implementation of monoclonal antibodies and nanobodies
In the past decades, the mainstay of systemic therapy for solid and haematological malignancies was chemotherapy; nevertheless this modality has the drawbacks such as drug resistance and eliciting sever cytotoxicity in the ...