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Association between serum kalirin levels and the KALRN gene rs9289231 polymorphism in early-onset coronary artery diseas
(2018)
Background: Recently, rs9289231 genetic variations of kalirin (KALRN) have been introduced as potential genetic markers for coronary artery disease (CAD). However, the influence of KALRN single-nucleotide polymorphisms ...
Reversion of Multidrug Resistance by Co-Encapsulation of Doxorubicin and Metformin in Poly(lactide-co-glycolide)-d-?-tocopheryl Polyethylene Glycol 1000 Succinate Nanoparticles.
(2018)
P-glycoprotein (P-gp) mediated multidrug resistance (MDR) has been recognized as the main obstacle against successful cancer treatment. To address this problem, co-encapsulated doxorubicin (DOX) and metformin (Met) in a ...
Polymorphism rs9939609 of Fat Mass and obesity-associated gene correlation with Leptin level of obese women suffered from type 2 diabetes.
(2017)
Background Recent studies reported that Fat Mass and obesity-associated gene (FTO) single nucleotides polymorphisms (SNPs), especially rs9939609, have association with obesity and type 2 diabetes mellitus. On the other ...
Cytoprotection, proliferation and epidermal differentiation of adipose tissue-derived stem cells on emu oil based electrospun nanofibrous mat.
(2017)
Electrospun nanofibrous scaffolds containing natural substances with wound healing properties such as Emu oil (EO) may have a great potential for increasing the efficiency of stem cell-based skin bioengineering. For this ...
Association between C-reactive protein and HbA1C among patients with type 2 diabetes mellitus
(2007)
Background: Type 2 diabetes mellitus is a common metabolic disorder witht increasing prevalence is increasing worldwide. C-Reactive Protein (CRP) is a marker of systemic inflammation and an independent risk factor for ...
New Developments in Pichia pastoris Expression System, Review and Update.
(2018)
Although Pichia pastoris is an outstanding host among conventional expression systems for production of recombinant proteins, a new interest have been emerged to this system due to the inherent advantages and new developments ...
Curcumin Affects Adipose Tissue-Derived Mesenchymal Stem Cell Aging Through TERT Gene Expression.
(2018)
Aging and losing cell survival is one of the main problems in cell therapy. Aging of Mesenchymal Stem Cells (MSCs) is associated with a rise in intracellular reactive oxygen species, decrease in telomerase reverse transcriptase ...
Chrysin Alters microRNAs Expression Levels in Gastric Cancer Cells: Possible Molecular Mechanism.
(2017)
Background Gastric carcinoma still remains the second most common cause of cancer mortality in the world. Chrysin, as a flavone, has showed cancer chemopreventive activity. The cellular and molecular mechanisms of chrysin ...
Effect of Culture Condition Variables on Human Endostatin Gene Expression in Escherichia coli Using Response Surface Methodology.
(2016)
Recombinant human endostatin (rhES) is an angiogenesis inhibitor used as a specific drug for the treatment of non-small-cell lung cancer. As mRNA concentration affects the recombinant protein expression level, any factor ...
Biomimetic synthesis of silver nanoparticles using Matricaria chamomilla extract and their potential anticancer activity against human lung cancer cells
(2018)
Herbs having various natural substances can be utilized for the biosynthesis of Silver nanoparticles (AgNPs) and act as a stable, reliable and biocompatible alternative instead of the current physical and chemical approaches. ...