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The effect of different coating materials on the prevention of powder bounce in the next generation impactor.
(2018)
In the process of quality control of pulmonary drug delivery products, aerosolization efficiency is mainly determined using impactors, e.g. next generation impactor (NGI). However, particle bounce may interfere with the ...
Synthesis of a novel polymeric magnetic solid phase extraction adsorbent for selective extraction of amphetamine from urine samples coupled with high performance liquid chromatography.
(2018)
A novel pH-responsive block copolymer (Poly ethylene glycol-b-poly (N,N-dimethylaminoethylmethacrylate-co-maleic acid) was designed for the decoration and stabilization of magnetic nanoparticles (MNPs) as an efficient ...
Application of Graphene and its Derivatives in Cancer Diagnosis and Treatment.
(2017)
Although chemotherapies are successful in some cases, systemic toxicity could be simultaneously observed due to the lack of drugs selectivity to cancerous tissues, leading to the failure of the chemotherapies. Furthermore, ...
BSA/Chitosan Polyelectrolyte Complex: A Platform for Enhancing the Loading and Cancer Cell-Uptake of Resveratrol
(2018)
The ultimate goal of cancer therapy is to kill as many cancerous cells while minimizing damage to the normal cells nearby. However, conventional chemotherapy suffers from drug resistance and lack of selectivity and ...
Effect of a Probiotic Preparation on Ventilator-Associated Pneumonia in Critically Ill Patients Admitted to the Intensive Care Unit: A Prospective Double-Blind Randomized Controlled Trial.
(2018)
Ventilator-associated pneumonia (VAP) occurs as a life-threatening complication in critically ill mechanically ventilated patients. Probiotic administration may modify the gut microbiota; however, whether this modification ...
Bioemulsifiers Derived from Microorganisms: Applications in the Drug and Food Industry.
(2018)
Emulsifiers are a large category of compounds considered as surface active agents or surfactants. An emulsifier acts by reducing the speed of chemical reactions, and enhancing its stability. Bioemulsifiers are known as ...
Fabrication of all-trans-retinoic acid-loaded biocompatible precirol: A strategy for escaping dose-dependent side effects of doxorubicin.
(2017)
Drug delivery-based nanoparticles have been emerged to be an alternative and efficient approach to cancer therapy compared to conventional systems. Here, we investigated the role of all-trans retinoic acid (ATRA) formulated ...
Folate-Targeted Nanostructured Lipid Carriers (NLCs) Enhance (Letrozol) Efficacy in MCF-7 Breast Cancer Cells
(2016)
Objective: Targeted-drug-delivery based lipid nanoparticles has emerged as a new and effective approach in cancer
chemotherapy. Here, we investigated the ability of folate-modified nanostructured lipid carriers (NLCs) to ...
Combination of solvent displacement and wet ball milling techniques for size reduction of celecoxib
(2016)
Background: The objective of the present study was to investigate the combinative effect of ball milling and solvent displacement method on size reduction of Celecoxib particles. Celecoxib is a poorly water soluble ...
Antioxidant reserve of the lungs and ventilator-associated pneumonia: A clinical trial of high dose selenium in critically ill patients.
(2018)
To evaluate the effect of supplemental selenium administration on the incidence of ventilator-associated pneumonia (VAP) in critically ill patients.Ninety-nine mechanically ventilated patients were randomized to receive ...