Now showing items 1-10 of 118
Prognostic factors in 1,138 Iranian colorectal cancer patients
Background and aim: The incidence of colorectal cancer is increased in Iran in recent years and colorectal cancer is the fourth most common cancer in both sexes. The aim of this study is to define the prognostic factors ...
Inhibition of c-REL using siRNA increased apoptosis and decreased proliferation in pre-B ALL blasts: Therapeutic implications
The c-Rel transcription factor is a unique member of the NF-kB family that has a role in apoptosis, proliferation and cell survival. Overexpression of c-Rel is detected in many human B cell tumors, including B-cell leukemia ...
Prevalence of atherosclerosis in patients with inactive rheumatoid arthritis
Patients with rheumatoid arthritis (RA) exhibit higher cardiovascular morbidity and mortality than the general population. The common carotid artery intima-media thickness (CCA-IMT) measured by ultrasound is a validated ...
Calcitriol Started in the Donor, Expands the Population of CD4+CD25+ T Cells in Renal Transplant Recipients
Objectives: Alloreactive T cells recognize antigens via direct and indirect pathways. The competency of costimulatory molecules on antigen-presenting cells (APC) is important. An active form of vitamin D (1,25(OH)2D3, ...
Joint association of complement component 3 and CC-cytokine ligand2 (CCL2) or complement component 3 and CFH polymorphisms in age-related macular degeneration
Background: To determine the joint effect of complement component 3(C3 R102G) with CC-cytokine ligand2 (CCL2-2518) or complement factor H (CFH) Y402H polymorphisms on advanced age-related macular degeneration (AMD). Methods: ...
Long-term dysphagia due to bronchogenic cyst of the esophagus
[No abstract available]
Comparing the effect of aromatase inhibitor (letrozole) + cabergoline (Dostinex) and letrozole alone on uterine myoma regression,a randomized clinical trial
Objective To evaluate the effect of letrozole in combination with cabergoline and letrozole alone on regression of symptomatic uterine myomas in women of reproductive age. Design Randomized controlled clinical trial. Setting ...
The Wnt/?-catenin signaling in endometriosis, the expression of total and active forms of ?-catenin, total and inactive forms of glycogen synthase kinase-3?, WNT7a and DICKKOPF-1
OBJECTIVES: The cyclical changes in proliferation and differentiation of endometrial cells are regulated by estrogen and progesterone via modulating Wnt/?-catenin signaling. Imbalance in the expression of estrogen and ...
Lack of association of CASC8 rs1447295 with colorectal cancer in Iranian population: A multicenter case-control study
Several studies reported the potential role of the rs1447295 polymorphism in susceptibility to cancer. This variant located in the cancer susceptibility candidate 8 (CASC8) is a long noncoding RNA (lnRNA) gene and does not ...