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The health status of the elderly population of Iran in 2012
(2015)
Background: With advancing age comes dramatic increase in the incidence of chronic diseases, disabilities, and mental problems. This study was conducted to epidemiologically describe the health status of the elderly ...
Inhibition of c-REL using siRNA increased apoptosis and decreased proliferation in pre-B ALL blasts: Therapeutic implications
(2017)
The c-Rel transcription factor is a unique member of the NF-kB family that has a role in apoptosis, proliferation and cell survival. Overexpression of c-Rel is detected in many human B cell tumors, including B-cell leukemia ...
Prevalence of atherosclerosis in patients with inactive rheumatoid arthritis
(2015)
Patients with rheumatoid arthritis (RA) exhibit higher cardiovascular morbidity and mortality than the general population. The common carotid artery intima-media thickness (CCA-IMT) measured by ultrasound is a validated ...
Resistance to single-agent chemotherapy and its risk factors in low-risk gestational trophoblastic neoplasms
(2015)
Aim Gestational trophoblastic neoplasm (GTN) is a rare disease which is classified into high- and low-risk groups. While the high-risk patients require combination therapy, the low-risk groups respond to single-agent ...
Major components of metabolic syndrome and nutritional intakes in different genotype of UCP2 -866G/A gene polymorphisms in patients with NAFLD
(2016)
Background: It has been suggested that dietary modifications in combination with genetic predisposition play an important role in the pathogenesis of NAFLD. In the current study we aimed to investigate the major components ...
Joint association of complement component 3 and CC-cytokine ligand2 (CCL2) or complement component 3 and CFH polymorphisms in age-related macular degeneration
(2017)
Background: To determine the joint effect of complement component 3(C3 R102G) with CC-cytokine ligand2 (CCL2-2518) or complement factor H (CFH) Y402H polymorphisms on advanced age-related macular degeneration (AMD). Methods: ...
Insulin resistance and ? cell function in patients with ?-thalassemia major
(2015)
Iron overload is a common finding in chronically transfused ?-thalassemia major (?-TM) patients with possible effect on ? cell function and insulin resistance. In this study we aimed to evaluate glucose metabolism, insulin ...
Effect of diet based on the principles of Iranian traditional medicine on cirrhosis (a clinical trial)
(2016)
Objectives Cirrhosis is associated with morbidity and mortality worldwide. Iranian traditional medicine (ITM) focused on nutritional intervention in order to improve liver function. The aim of this study was to assess the ...
Prevalence of hookah smoking in relation to religiosity and familial support in college students of Tabriz, Northwest of Iran
(2014)
Background: Hookah smoking has increased worldwide especially among youth and young adults and has been identified as an emerging threat to public health. The aim of the present study was to determine the prevalence of ...
Comparing the effect of aromatase inhibitor (letrozole) + cabergoline (Dostinex) and letrozole alone on uterine myoma regression,a randomized clinical trial
(2017)
Objective To evaluate the effect of letrozole in combination with cabergoline and letrozole alone on regression of symptomatic uterine myomas in women of reproductive age. Design Randomized controlled clinical trial. Setting ...