Now showing items 1-10 of 13
Direct and indirect medical costs of functional constipation: A population-based study
Background Constipation causes a large number of medical visits each year and imposes significant financial toll on healthcare systems worldwide. So the present communitybased study was conducted in order to estimate ...
Four novel germline mutations in the MLH1 and PMS2 mismatch repair genes in patients with hereditary nonpolyposis colorectal cancer
Background: Hereditary nonpolyposis colorectal cancer (HNPCC) is the most common cause of early onset hereditary colorectal cancer. In the majority of HNPCC families, microsatellite instability (MSI) and germline mutation ...
Glutathione-S-transferase M1, T1 and P1 gene polymorphisms in type I autoimmune hepatitis: A case-control study 
[No abstract available]
Association between MTHFR polymorphism (C677T) with nonfamilial colorectal cancer
The enzyme 5,10-methylene-tetrahydrofolate reductase (MTHFR) is linked to DNA methylation, synthesis, and repair. C677T is one of the most important polymorphisms in the MTHFR gene. The single nucleotide polymorphism C677T ...
Profile and frequency of p53 Gene alterations in gastritis lesions from Iran
Background: It has been frequently shown that p53 alterations have an important role in the development of gastric cancers but there is no data on p53 alteration in gastric cancer and its precancerous lesions from Iran ...
Prenatal screening and counseling in iran and ethical dilemmas
Objective: Prenatal screening has become an increasingly common procedure all over the world. It offers couples useful information relating to the health of their fetus, although it faces us with serious ethical dilemmas ...
Prognostic factors in 1,138 Iranian colorectal cancer patients
Background and aim: The incidence of colorectal cancer is increased in Iran in recent years and colorectal cancer is the fourth most common cancer in both sexes. The aim of this study is to define the prognostic factors ...
NOD2 exonic variations in Iranian Crohn's disease patients
Purpose The NOD2 gene is known to have a strong association with Crohn's disease, but different trends were reported in occurrence of NOD2 variants in distinct ethnicities. The aim of this study was to assess all exonic ...
Prevalence of multiple drug-resistant helicobacter pylori strains among patients with different gastric disorders in Iran
Emergence of multidrug-resistant (MDR) strains of Helicobacter pylori is a global health concern. This study was aimed to determine the frequency of MDR H. pylori strains in Iran. H. pylori isolates were obtained from ...
Mucins in neoplastic spectrum of colorectal polyps: Can they provide predictions?
Background: The significance of expression of different mucins in succession of malignant transformation of colorectal polyps is not determined yet. The aim of the present study was to determine the pattern of expression ...