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Association between MTHFR polymorphism (C677T) with nonfamilial colorectal cancer
The enzyme 5,10-methylene-tetrahydrofolate reductase (MTHFR) is linked to DNA methylation, synthesis, and repair. C677T is one of the most important polymorphisms in the MTHFR gene. The single nucleotide polymorphism C677T ...
Association between the 1793G>A MTHFR polymorphism and sporadic colorectal cancer in Iran
Background: It has been proposed that folate and polymorphisms of the enzyme methylenetetrahydrofolate reductase (MTHFR), which regulates influx of folate for methylation reactions for DNA synthesis and repair, are involved ...
Impact of EXO1 polymorphism in susceptibility to colorectal cancer
Background and Aim: One candidate gene for colorectal cancer (CRC) susceptibility is exonuclease 1 (EXO1). It is a member of RAD2 nuclease family, which plays a major role in mismatch repair, DNA replication, and recombination. ...
Mucins in neoplastic spectrum of colorectal polyps: Can they provide predictions?
Background: The significance of expression of different mucins in succession of malignant transformation of colorectal polyps is not determined yet. The aim of the present study was to determine the pattern of expression ...