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Lack of influence of TP53 Arg72Pro and 16bp duplication polymorphisms on risk of breast cancer in Iran.
TP53 is assumed to be a very important tumour suppressor gene, as illustrated by recent reports that have shown effects of its polymorphisms on breast cancer risk. Arg72Pro and PIN3(16bp duplication) polymorphisms are ...
Role of exon 7 PTEN Gene in Endometrial Carcinoma.
Endometrial carcinoma is the most common malignant tumor of the female genital tract and the fourth most common cancer in Iranian women after breast, colorectal and lung cancers. Various genetic alterations appear to be ...
Polymorphism of p53 gene codon 72 in endometrial cancer: correlation with tumor grade and histological type.
Endometrial cancer is the fourth most common cancer among women in developed countries. Patients with endometrial cancer may benefit from systemic chemotherapy alone or in combination with targeted therapies if the disease ...
The polymorphism of hypoxia-inducible factor-1a gene in endometrial cancer.
Endometral carcinoma is the most common malignant tumor of the female genital tract and the fourth most common cancer in women after breast, colorectal and lung cancers Hypoxia-inducible factor -1 (HIF-1) is a key transcription ...
Genetic Evidence for the Involvement of Variants at APOE, BIN1, CR1, and PICALM Loci in Risk of Late-Onset Alzheimer's Disease and Evaluation for Interactions with APOE Genotypes
Alzheimer's disease (AD) is the most common form of dementia in older population. Growing evidence of genetic background that predisposes individuals to AD has been reported as the risk factors in recent years. The Department ...
C-kit mutations in endometrial cancer: Correlation with tumor histologic type
Objective: Endometrial cancer is the fourth most common cancer among women in developed countries. Affected patients may benefit from systemic chemotherapy, alone or in combination with targeted therapies if the disease ...